Blood normally circulates through endothelium lined blood vessels. When a blood vessel is severed, a blod clot (thrombus) forms as a part of hemostasis, the physiologic response that stops bleeding.
Summary of the Steps involved in Hemostasis:
Summary of the Steps involved in Hemostasis:
- Vasoconstriction mediated by serotonin (5-HT), thromboxane (TXA2),etc.
- Exposure of collagen on the wall of blood vessel leading to platelet aggregation and formation of white plug or primary hemostatic plug.
- Adhesion of platelet to blood vessel wall leads to activation of platelets resulting in release of ADP and TXA2.
- ADP and TXA2 further facilitates aggregation of platelets by increasing platelet stickiness.
- Platelet activation also leads to initiation of blood clotting (injured tissue also releases thromboplastin)
- Fibrinization of primary platelet plug leads to formation of strong secondary platelet plug.
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Thank you. This video was so helpful in studying for my physiology exam on blood. I so appreciated how you worded at the end - thanking Jesus Christ for being the one to lead you to think of others, not just yourself. I've taken that same principle and applied it to making sample tests to study and then asking my classmates if they wanted them to help them study. Thank you for letting Christ use you to build up the body (no pun intended).
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